Tamiflu May Not be Enough

According to Steven Gamblin and his co-workers at the National Institute for Medical Research in London and the University of St Andrews, going against the bird flu with Tamiflu may not be enough.

Mutations arising which have a selection advantage are very quickly exploited [by the virus],’ Gamblin says. ‘Our study suggests that stockpiling a single drug, oseltamivir, might not be sufficient if we are faced with a pandemic.

This was proven as molecular pictures of another drug, zanamivir, may be more effective than Tamiflu. Zanamivir can block the active site of the mutant enzyme.

The reason why nations are stock piling on Tamiflu is because it is cheaper.

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